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Your Position: Home > IL-2 R beta & IL-2 R gamma

IL-2 R beta & IL-2 R gamma

Brief Information

Name:Interleukin-2 receptor beta chain
Target Synonym:IL2RB,IMD63,IL-2RB,p75,CD122,Interleukin 2 Receptor Subunit Beta,Interleukin-15 Receptor Subunit Beta,Interleukin 15 Receptor, Beta,Interleukin 2 Receptor, Beta,IL-2R Subunit Beta,CD122 Antigen,P70-75,IL15RB,High Affinity IL-2 Receptor Beta Subunit,Interleukin-2 Receptor beta Subunit,Interleukin-2 receptor subunit beta,IL-2 receptor subunit beta,High affinity IL-2 receptor subunit beta
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:12
Lastest Research Phase:Phase 3 Clinical

Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
ILG-M82F3 Mouse Biotinylated Mouse IL-2 R beta & IL-2 R gamma Protein, Fc,Avitag™
ILG-M82F3-sds
ILG-C5284 Cynomolgus Cynomolgus IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)
ILG-C5284-structure
ILG-C5284-sds
ILG-R82F3 Rhesus macaque Biotinylated Rhesus macaque IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc,Avitag™&Fc,Avitag™ (MALS verified)
ILG-R82F3-structure
ILG-R82F3-sds
ILG-R5284 Rhesus macaque Rhesus macaque IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)
ILG-R5284-structure
ILG-R5284-sds
CHEK-ATF136 Human Human IL-2 R beta/IL-2 R gamma (Luc) HEK293 Reporter Cell
ILG-M5254 Mouse Mouse IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)
ILG-M5254-structure
ILG-M5254-sds
ILG-H5283 Human Human IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)
ILG-H5283-structure
ILG-H5283-sds
ILG-R5283 Rat Rat IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)
ILG-R5283-sds
ILG-M5283 Mouse Mouse IL-2 R beta&IL-2 R gamma Heterodimer Protein, His Tag&Twin-Strep Tag (MALS verified)
ILG-M5283-structure
ILG-M5283-sds
ILG-H82F3 Human Biotinylated Human IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc,Avitag™&Fc,Avitag™ (MALS verified)
ILG-H82F3-structure
ILG-H82F3-sds
ILG-H5254 Human Human IL-2 R beta&IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)
ILG-H5254-structure
ILG-H5254-sds
ACRO Quality

Part of Bioactivity data

CHEK-ATF136-Cell-based assay
 IL-2 R beta & IL-2 R gamma FACS

Co-expression analysis of human IL-2 R beta and IL-2 R gamma on Human IL-2 R beta/IL-2 R gamma (Luc) HEK293 Reporter Cell by FACS.
Cell surface staining was performed on Human IL-2 R beta/IL-2 R gamma (Luc) HEK293 Reporter Cell or negative control cell using PE-labeled anti-IL-2 R beta antibody and APC-labeled anti-IL-2 R gamma antibody.

ILG-H5254-SPR
 IL-2 R beta & IL-2 R gamma SPR

Human IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILG-H5254) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human IL-2, Tag Free with an affinity constant of 0.279 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

ILG-C82F4-BLI
 IL-2 R beta & IL-2 R gamma BLI

Loaded Biotinylated Cynomolgus IL-2RB&IL-2RG, Fc,Avitag&Fc,Avitag (Cat. No. ILG-C82F4) on SA Biosensor, can bind Human IL-2, Tag Free with an affinity constant of 2.34 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Customer Reviews

IL-2 R beta & IL-2 R gamma Molecule Synonym Name

IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG

IL-2 R beta & IL-2 R gamma Molecule Background

Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

IL-2 R beta & IL-2 R gamma References

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