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Your Position: Home > Glycoprotein (RABV)

Glycoprotein (RABV)

Brief Information

Name:Thrombospondin 1
Target Synonym:TSP,Glycoprotein G,THBS1,Thrombospondin-1p180,TSP1,Thrombospondin-P50,Thrombospondin-1,THBS-1,TSP-1,THBS,Thrombospondin 1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 1 Clinical

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ACRO Quality

Part of Bioactivity data

RAG-M305-ELISA
 Glycoprotein (RABV) ELISA

Immobilized Rabies virus Glycoprotein, His Tag (Cat. No. RAG-V55H5) at 1 μg/mL (100 μL/well) can bind Mouse Glycoprotein G Antibody, Mouse IgG1 (523-11) (Cat. No. RAG-M305) with a linear range of 0.1-2 ng/mL (QC tested).

RAG-V55H5-MALS-HPLC
Glycoprotein (RABV) MALS images

The purity of Rabies virus Glycoprotein G, His Tag (Cat. No. RAG-V55H5) is more than 85% and the molecular weight of this protein is around 165-195 kDa verified by SEC-MALS.

Synonym Name

Glycoprotein

Background

Rabies virus (RABV), scientific name Rabies lyssavirus, is a deadly neurotropic virus that causes rabies in humans and animals. Rabies virus has an extremely wide host range and its transmission most often occur through the saliva of animals. Without intervention prior to disease progression, rabies has the highest case fatality of any infectious disease. RABV contains a single-stranded negative-sense RNA genome that encodes five structural proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and RNA-dependent RNA polymerase (L). Among these viral proteins, the RABV glycoprotein (RABV-G) is a pivotal player mediating virus entry and the major target of neutralizing antibodies, thus a key factor for vaccine and drug design.

Clinical and Translational Updates

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