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OV16

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ACRO Quality

Part of Bioactivity data

OV6-V81G9-ELISA
OV16 MALS images

The purity of Biotinylated Onchocerca volvulus OV16 protein, Avi,GST Tag (Cat. No. OV6-V81G9) is more than 90% and the molecular weight of this protein is around 90-105 kDa verified by SEC-MALS.

Synonym Name

OV16,OV-16 antigen

Background

The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O. volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis. It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide. Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.

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