로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP Cytokines Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
There is no goods in the shopping cart !
My Cart|Secure Checkout
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > SDF-1

SDF-1

Brief Information

Name:C-X-C motif chemokine ligand 12
Target Synonym:Pre-B Cell Growth-Stimulating Factor,SDF1B,C-X-C Motif Chemokine Ligand 12,SDF1,SDF-1,Chemokine (C-X-C Motif) Ligand 12,Stromal Cell-Derived Factor 1,CXCL12,HSDF-1,SCYB12,C-X-C Motif Chemokine 12,IRH,TLSF,Chemokine CXCL12,TLSF-A,TLSF-B,SDF-1b,SDF-1a,Intercrine Reduced In Hepatomas,TPAR1,PBSF,HIRH,SDF1A
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:8
Lastest Research Phase:Phase 3 Clinical

Product ListCompare or Buy

Product> Filter Results
By Product Status:
By Product Category:
By Species:
By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
SD1-H5143 Human Human SDF-1 / CXCL12 Protein, His Tag
SD1-H5143-structure
SD1-H5143-sds
ACRO Quality

Synonym Name

SDF-1,CXCL12,hSDF-1,IRH,hIRH,PBSF,SDF1,SDF1A,SDF1B

Background

Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. Inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Plays a protective role after myocardial infarction. Induces down-regulation and internalization of ACKR3 expressed in various cells. Has several critical functions during embryonic development; required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Stimulates the proliferation of bone marrow-derived B-cell progenitors in the presence of IL7 as well as growth of stromal cell-dependent pre-B-cells

Clinical and Translational Updates

This web search service is supported by Google Inc.

totop
Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
Email
Email
order@acrobiosystems.com
Fax
Fax
+1 888-377-6111
Address
Address
1 Innovation Way, Newark, DE 19711, USA
linkedin twitter facebook youtube

Leave a message

Copyright © 2017 ACROBiosystems. All Rights Reserved
|Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap