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A35R

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Part of Bioactivity data

A3R-M575-SPR
A35R SPR

Monoclonal Anti-Monkeypox-A35R Antibody, Human IgG1 (6F11) (Cat. No. A3R-M575) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) A35R , His Tag (Cat. No. A3R-M52H3) with an affinity constant of 0.269 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
A3R-Y90-ELISA
A35R ELISA

Immobilized Monkeypox virus (strain Zaire-96-I-16) A35R Protein, His Tag (Cat. No. A3R-M52H3) at 2μg/mL (100μL/well) can bind Monoclonal Anti-Monkeypox -A35R Antibody, Mouse IgG1 (6F11) (Cat. No. A3R-Y90) with a linear range of 0.05-100 ng/mL (QC tested).

Protocol

Synonym Name

A35R

Background

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The cases are mostly in central and western Africa.  The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. The envelope glycoprotein A35R on the EV surface has been predicted to influence intercellular diffusion of virions.

Clinical and Translational Updates

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