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| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| DK1-H82F5 | Human | Biotinylated Human Dkk-1 Protein, Fc,Avitag™ |  |
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| DK1-H5258 | Human | Human Dkk-1 Protein, Fc Tag (MALS verified) |  |
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| DK1-M52H6 | Mouse | Mouse Dkk-1 Protein, His Tag |  |
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| DK1-H5221 | Human | Human Dkk-1 Protein, His Tag, premium grade |  |
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Human Dkk-1 Protein, Fc Tag (MALS verified) (Cat. No. DK1-H5258) inhibits Wnt induced TCF reporter activity in HEK293 cells. Human Dkk-1 inhibits a constant dose of 0.03 µg/mL of Wnt surrogate. The EC50 for this effect is 0.051 µg/mL.
Immobilized Mouse Dkk-1, His Tag (Cat. No. DK1-M52H6) at 5 μg/mL (100 μL/well) can bind Human LRP-5, Mouse IgG2a Fc Tag (Cat. No. LR5-H5254) with a linear range of 0.01-0.313 μg/mL (QC tested).
The purity of Human Dkk-1, Fc Tag (Cat. No. DK1-H5258) is more than 90% and the molecular weight of this protein is around 118-145 kDa verified by SEC-MALS.
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| RN-564 | RN-564; PF-4840082; PF-04840082 | Pfizer Inc | Details | ||
| Sirexatamab | DKN-01; LY-2812176 | Phase 2 Clinical | Eli Lilly And Company | Ovarian Neoplasms; Liver Neoplasms; Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Multiple Myeloma; Cholangiocarcinoma; Bile Duct Neoplasms; Colorectal Neoplasms; Uterine Neoplasms; Endometrial Neoplasms; Carcinosarcoma; Gallbladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular | Details |
| JS-015 | JS-015 | Phase 1 Clinical | Shanghai Junshi Biological Engineering Co Ltd | Solid tumours | Details |
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