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Your Position: Home > LILRA3

LILRA3

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Cat. No. Species Product Description Structure Purity Feature
LI3-H52H4 Human Human LILRA3 / CD85e Protein, His Tag
LI3-H52H4-structure
LI3-H52H4-sds
LI3-H82E0 Human Biotinylated Human LILRA3 / CD85e Protein, His,Avitag™
LI3-H82E0-structure
LI3-H82E0-sds
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Synonym Name

LILRA3,ILT6,LIR4,CD85e

Background

Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3) is also known as CD85 antigen-like family member E (CD85e), immunoglobulin-like transcript 6 (ILT-6), and leukocyte immunoglobulin-like receptor 4 (LIR-4) is a protein that in humans is encoded by the LILRA3 gene located within the eukocyte receptor complex on chromosome 19q13.4. Unlike many of its family, LILRA3 lacks a transmembrane domain, which contains 4 Ig-like C2-type (immunoglobulin-like) domains. LILRA3 acts as soluble receptor for class I MHC antigens. At the same time,LILRA3 can bind both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Also,LILRA3 can bind with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.

Clinical and Translational Updates

Related Molecule

ANGPTL7

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