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Your Position: Home > BDNF

BDNF

Brief Information

Name:Brain-derived neurotrophic factor
Target Synonym:Brain-Derived Neurotrophic Factor,Abrineurin,ANON2,Brain Derived Neurotrophic Factor,BULN2,ProBDNF,Neurotrophin
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:8
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
BDF-H5116 Human Human BDNF / Abrineurin Protein (E. coli), premium grade
BDF-H5116-structure
BDF-H5116-sds
BDF-H5219 Human Human BDNF / Abrineurin Protein (HEK293), premium grade
BDF-H5219-structure
BDF-H5219-sds
ACRO Quality

Part of Bioactivity data

BDF-H5219-MALS-HPLC
BDNF ELISA

Immobilized Human BDNF, premium grade (Cat. No. BDF-H5219) at 1 μg/mL (100 μL/well) can bind Human TrkB, His Tag (Cat. No. NT2-H5228) with a linear range of 2-78 ng/mL (QC tested).

Protocol

Synonym Name

BDNF,ANON2,BULN2,Abrineurin

Background

Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent).

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