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Your Position: Home > BTN3A1

BTN3A1

Brief Information

Name:Butyrophilin subfamily 3 member A1
Target Synonym:BTF5,BTN3A1,CD_antigen,BTN3.1,BT3.1,DJ45P21.3 (Butyrophilin, Subfamily 3, Member A1),Butyrophilin, Subfamily 3, Member A1,CD277 Antigen
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
BT1-H52H4 Human Human BTN3A1 / CD277 Protein, His Tag, active dimer (MALS verified)
BT1-H52H4-sds
BT1-H82E4 Human Biotinylated Human BTN3A1 / CD277 Protein, His,Avitag™
BT1-H82E4-structure
BT1-H82E4-sds
BT1-H82F7 Human Biotinylated Human BTN3A1 / CD277 Protein, Fc,Avitag™
BT1-H82F7-structure
BT1-H82F7-sds
BT1-H5255 Human Human BTN3A1 / CD277 Protein, Fc Tag (MALS verified)
BT1-H5255-structure
BT1-H5255-sds
ACRO Quality

Part of Bioactivity data

BT1-H5255-MALS-HPLC
BTN3A1 MALS images

The purity of Human BTN3A1, Fc Tag (Cat. No. BT1-H5255) is more than 90% and the molecular weight of this protein is around 95-115 kDa verified by SEC-MALS.

BT1-H82E4-ELISA
BTN3A1 ELISA

Immobilized Anti-BTN3A123 Antibody, Mouse IgG1 at 1 μg/mL (100 μL/well) can bind Biotinylated Human BTN3A1 Protein, His,Avitag (Cat. No. BT1-H82E4) with a linear range of 0.1-4 ng/mL (QC tested).

Protocol

Synonym Name

BTN3A1,CD277,BTF5

Background

Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Clinical and Translational Updates

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