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| Project Name | Project Stage | Molecule Type | Host Species | Therapeutic Area | Indications |
| BAFFR&CD3 BsAb - 01 | PCC | Hematological Malignancy,AutoImmunity | Blood tumor,Autoimmune disease |
5e5 of anti-BAFFR CAR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human BAFFR Protein, His Tag (Cat. No. BAR-HP2H6) and negative control protein respectively. PE signal was used to evaluate the binding activity (QC tested).
Immobilized Human BAFF Protein, Fc Tag (Cat. No. BAF-H5261) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human BAFFR Protein, Llama IgG2b Fc Tag (Cat. No. BAR-H5258) with an affinity constant of 44.5 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| AUR-200 | AUR-200 | Phase 1 Clinical | Thunderbolt Pharma Inc | Autoimmune Diseases | Details |
| ESG-206 | ESG-206 | Phase 1 Clinical | Shanghai Escugen Biotechnology Co Ltd | Lymphoma | Details |
| Ianalumab | VAY-736; NOV-5 | Phase 3 Clinical | Morphosys Ag, Novartis Pharma Ag | Lymphoma, B-Cell, Marginal Zone; Hematologic Neoplasms; Sjogren's Syndrome; Idiopathic Pulmonary Fibrosis; Arthritis, Rheumatoid; Lupus Nephritis; Multiple Sclerosis; Primary mediastinal B cell lymphoma; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lupus Erythematosus, Systemic; Hepatitis, Autoimmune; Lymphoma, Non-Hodgkin; Pemphigus; Leukemia, Lymphocytic, Chronic, B-Cell | Details |
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