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Your Position: Home > LILRA2

LILRA2

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Cat. No. Species Product Description Structure Purity Feature
LI2-H52H3 Human Human LILRA2 / CD85h / ILT1 Protein, His Tag
LI2-H52H3-structure
LI2-H52H3-sds
LI2-H82E9 Human Biotinylated Human LILRA2 / CD85h / ILT1 Protein, His,Avitag™
LI2-H82E9-structure
LI2-H82E9-sds
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Synonym Name

ILT1, LIR7, CD85H, LIR-7, LILRA2, ILT1CD85H, CD85h, ILT1, ILT-1, ILT1CD85H, CD85h antigen, CD85 antigen-like family member H

Background

LILRA2 (Leukocyte immunoglobulin like receptor A2), also known as CD85H and LIR7 (Leukocyte immunoglobulin-like receptor 7). It belongs to the subfamily A class of LIR receptors (LILRAs), which are single-pass type I transmembrane proteins with 2-4 extracellular Ig-like domains, a transmembrane domain (TM), and a short cytoplasmic tail.  LILRA2 contains 4 Ig-like C2 type domains in the extracellular region. LILRA2 does not bind class I MHC antigens. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response.

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