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2e5 of Overexpressed-CD24 CAR-293 cells were stained with 100μL of 1:10 dilution of PE-Labeled Human Siglec-10 Protein, His Tag(recommended for neutralizing assay)(Cat. No. SI0-HP2E5)and negative control protein respectively, washed and analyzed with FACS (QC tested).
Loaded Human CD32a (R167), His Tag (Cat. No. CDA-H5221) on HIS1K Biosensor, can bind Human Siglec-10, Fc (L118A, G120A, E201A) Tag (Cat. No. SI0-H5255) with an affinity constant of 37.5 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| AI-071 | AI-071 | Phase 1 Clinical | Oncoimmune-Guangzhou | Coronavirus Disease 2019 (COVID-19); Neoplasms | Details |
| EXO-CD24 | Phase 2 Clinical | Tel-Aviv Sourasky Medical Center | Coronavirus Disease 2019 (COVID-19) | Details | |
| Efprezimod alfa | CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 | Phase 3 Clinical | Oncoimmune Inc | Leukemia; Hematopoietic stem cell transplantation (HSCT); HIV Infections; Solid tumours; Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19); Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Dyslipidemias; Leukemia, Myeloid, Acute; Melanoma | Details |
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