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GENIUS™ Nuclease, premium grade is designed for preclinical stage, has more comprehensive QC testing (such as HCP and so on) and tighter specifications based on the following GENIUS features.
GENIUS™ Nuclease, premium grade has the same activity and performance with GMP Grade Nuclease, which enables a seamless transition from preclinical development to clinical phases. By using GENIUS™ Nuclease, premium grade in your development phase you can easily transit into clinical and commercial phases and avoid needing to amend your manufacturing process and undertake comparability studies.
● Generally usable: Generally usable for removing all forms of DNA and RNA from biological products, reducing viscosity and preventing cell clumping.
● Efficient: Efficient reaction, rapid degradation, reduce processing time.
● Native: Native structure, tag free, the enzyme activity is more guaranteed.
● Ideal: Ideal for DNA and RNA clearance
● Ultra pure: Ultra pure: High purity and activit
● Specific: Specific nuclease, no protease activity
Elimination of nucleic acids from biologics, suitable for samples with 0-200 mM salt in presence of 2-10 mM Mg++
• viral vaccine development process
• viral vector development process for cell and gene therapy (CGT)
• Other biologics development processes
>95% as determined by SDS-PAGE.
>99% as determined by SEC-HPLC.
Supplied as 0.2 μm filtered solution in 20 mM Tris, 20 mM NaCl, 2 mM MgCl2, pH8.0 with glycerol as protectant.
Contact us for customized product form or formulation.
This product is supplied and shipped with dry ice, please inquire the shipping cost.
This product is stable after storage at:
The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of GENIUS™ Nuclease, premium grade (Cat. No. NUE-S5119) was greater than 99% as determined by SEC-HPLC.
Specific activity for GENIUS™ Nuclease, premium grade is measured under standard assay conditions. The specific activity of GENIUS™ Nuclease, premium grade is > 1.2 x 10^6 units/mg protein (QC tested). One unit will digest sonicated salmon sperm DNA to acid-soluble oligonucleotides equivalent to a ΔA260 of 1.0 in 30 min at pH 8.0 at 37 °C, which corresponds approximately to complete digestion of 37 μg DNA. Note that 1 KU=1000 units.
GENIUS™ Nuclease, premium grade shows high specific activity.
The specific activity shows that GENIUS™ Nuclease, premium grade is stable at 4°C for 14 days.
The specific activity shows that GENIUS™ Nuclease, premium grade is stable at 37°C for 48 hours.
Price(USD) : $330.00
Price(USD) : $1260.00
Price(USD) : Inquire
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