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Your Position: Home > Antibody > CD68 > HGS-S262

Recombinant Monoclonal Anti-CD68 Antibody, Rabbit (2D8)

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  • Background
    Recombinant Monoclonal Anti-CD68 Antibody, Rabbit (2D8) is a CD68 primary antibody for IHC application. Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • Key parameter
    Host SpeciesRabbit
    IsotypeIgG
    Clone2D8
    ApplicationIHC
    Property1:1000
    StateLiquid
    Positive ControlHuman Tonsil Tissues
    ClonalityMonoclonal
    Research FieldCancer Drug Targets
    SourceRabbit
    SynonymDKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1
  • Experiment Protocol
  • Storage
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. The shelf life is 30 days from the date of opening.
Typical Data
Control Sample
 CD68 CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S262 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Cancer Sample
 CD68 CANCER SAMPLE CD68 CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S262 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • Clinical and Translational Updates

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