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This protein carries no "tag".
The protein has a calculated MW of 13.2 kDa. The protein migrates as 13 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
>95% as determined by SDS-PAGE.
Lyophilized from 0.22 μm filtered solution in 20 mM Citric acid, pH2.2 with trehalose as protectant.
Contact us for customized product form or formulation.
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
Human BMP-4 (improved sequence) Protein, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
Human BMP-4 (improved sequence) Protein, premium grade (Cat. No. BM4-H5118) stimulates proliferation of Human BMP (Luc) HEK293 Reporter Cell (Cat. No. CHEK-ATF188). The specific activity of Human BMP-4 (improved sequence) Protein, premium grade is > 1.9 x 10^3 U/mg (QC tested).
Human BMP-4 (improved sequence) Protein, premium grade (Cat. No. BM4-H5118) could significantly induce iPSC derived HSPC differentiation, with high expression of CD34 and CD45 (HSPC markers) by flow cytometry analysis and the increase of viable numbers of CD34+ CD45+ cells by cell counting. NC: H2O treatment (Routinely tested).
Human BMP-4 (improved sequence) Protein, premium grade (Cat. No. BM4-H5118) could significantly inhibit endoderm cell marker FOXA2 expression and promote mesoderm cell marker Brachyury expression from iPSC differentiation by FACS analysis. NC: CHIR99021; ACRO: CHIR99021+BMP4 treatment (30 ng/mL) (Routinely tested).
Human BMP-4 (improved sequence) Protein, premium grade (Cat. No. BM4-H5118) could significantly inhibit endoderm cell marker FOXA2 expression and promote mesoderm cell marker Brachyury expression from iPSC differentiation by immunofluorescence staining. NC: CHIR99021; ACRO: CHIR99021+BMP4 treatment (30 ng/mL) (Routinely tested).
The Cell based assay shows batch-to-batch consistency between Acro's GMP and PG BMP-4 (improved sequence).
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Emerging VoCs, Omicron, Delta, Beta, Alpha mutants and so on, including RBD, S trimer, S1, NTD, NP, etc. These mutants are of high purity and bioactivity and can be used to evaluate the efficacy of the antibodies and vaccination.
ACROBiosystems developed a series of GMP grade cytokines under the GMP grade quality management system. Those products are all suitable for T/NK cell generation, activation, and proliferation in cell therapy research.
50+ targets designed for CAR detection, including PE/FITC/biotin labeled proteins. The key reagents for CD19 and BCMA were FDA DMF filed which can support your IND, NDA and BLA process.
GMP grade cytokines, reagents for cell activation, gene edition, DNA/RNA removal, etc. Particularly focus on product design, quality control and solution-based support to link each phase of your cell and gene therapy journey.
Full length multi-pass TPs with stabilized structure and high bioactivity for immunization, antibody screening, cell based assay and CAR detection, including hot CD20, Claudin 18.2， CD133, GPRC5D，CCR8, CCR5, etc.
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A series of immune checkpoints including classic co-inhibitory and co-stimulatory receptors. The comprehensive catalog contains 100+ targets with various species and tags, and the high-quality proteins are in good batch-to-batch consistency.
To meet the needs of ADCs development, ACROBiosystems can provide: A variety of high-quality target proteins; MMPs/Cathepsin/uPA for cleavable linker; Anti-payload antibodies & anti-idiotypic antibodies for immunogenicity and PK analysis; SPR/BLI analytical and ADA development service.
Comprehensive collection of Fc receptor proteins, including their common variants, which can help expedite your antibody development.
The MABSOL biotinylated protein collection includes more than a hundred commonly studied drug targets and biomarker proteins.
Comprehensive cytokines including IL families, growth factors, chemokines, TNFs, etc. These products are HEK293 expressed and nearly in authentic structure, high purity and bioactivity, cell based assay/SPR/BLI verified.
To support preclinical/clinical immunogenicity and PK analysis, ACROBiosystems has developed a series of high-affinity anti-idiotypic antibodies. Our pipeline covers five hot targets including adalimum*b, rituxim*b, cetuxim*b, trastuzum*b, and bevacizum*b.
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