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Your Position: Home > Protein > Tau > TAU-H5119

Human Tau-412 / 1N4R Protein, Tag Free, low Endotoxin (MALS verified)

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  • Synonym
    DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU
  • Source
    Human Tau-412 Protein, Tag Free(TAU-H5119) is expressed from E. coli cells. It contains AA Met 1 - Leu 412 (Accession # P10636-7).
    Predicted N-terminus: Met
  • Molecular Characterization
    Tau Structure

    This protein carries no "tag".

    The protein has a calculated MW of 43 kDa. The protein migrates as 43 kDa,45 kDa and 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 0.01 EU per μg by the LAL method / rFC method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
SDS-PAGE
Tau SDS-PAGE

Human Tau-412 Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
Tau MALS images

The purity of Human Tau-412 Protein, Tag Free (Cat. No. TAU-H5119) is more than 90% and the molecular weight of this protein is around 35-55 kDa verified by SEC-MALS.

Bioactivity-ELISA
 Tau ELISA

Immobilized Human Tau-412 Protein, Tag Free (Cat. No. TAU-H5119) at 1 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.06-8 ng/mL (QC tested).

  • Background
    This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
  • Clinical and Translational Updates

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ETA des produits en stock: 2 jours ouvrables

Drug Development Status

  • Number of Launched Drugs:1 Details
  • Number of Drugs in Clinical Trials:36 Details
  • Latest Research Phase:Approved

Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

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