로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Antibody > IgG4 Fc > IG4-MY2180

Monoclonal Anti-Human IgG4 Fc Antibody, Mouse IgG2a (1A10) (MALS verified)

Order Now

  • Source

    Monoclonal Anti-Human IgG4 Fc Antibody, Mouse IgG2a (1A10) is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.

  • Clone

    1A10

  • Species

    Mouse

  • Isotype

    Mouse IgG2a | Mouse Kappa

  • Conjugate

    Unconjugated

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Human

  • Immunogen

    Recombinant Human IgG4 Fc is expressed from human 293 cells.

  • Specificity

    Specifically recognizes IgG4 Fc.

  • Application
    ApplicationRecommended Usage
    ELISA0.5-500 ng/mL
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Cross Verification

    This product No cross-reactivity in ELISA with
    UreluMab, Human IgG4.
    Monoclonal Anti-Human LAG3 Antibody, Human IgG4 (S108P).
    Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG3 (AS35) (Cat. No. SPD-S67).
    Monoclonal Anti-IFNγ Antibody, Human IgG1 (8C5F8) (Cat. No. IFN-M412).
    Anti-SARS-CoV-2 Spike RBD Broadly Neutralizing Antibody, Human IgG2 (AM359b) (Cat. No. SPD-M400a).
    Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgA2 (AM130) (Cat. No. SPD-M196b).
    Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgA1 (AM130) (Cat. No. S1N-M164).
    Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Cynomolgus IgG1 (AM122) (Cat. No. SPD-M201).
    Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) (Cat. No. ERN-MY2012b).
    Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgM (AM122) (Cat. No. SPD-M162).
    The antibody does not recognize S108P mutation.
    The antibody does not recognize S108P mutation protein.

SDS-PAGE
IgG4 Fc SDS-PAGE

Monoclonal Anti-Human IgG4 Fc Antibody, Mouse IgG2a (1A10) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
IgG4 Fc MALS images

The purity of Monoclonal Anti-Human IgG4 Fc Antibody, Mouse IgG2a (1A10) (Cat. No. IG4-MY2180) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

Bioactivity-ELISA
 IgG4 Fc ELISA

Immobilized Anti-CD4 Antibody (Ibalizumab-IgG4) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human IgG4 Fc Antibody, Mouse IgG2a (1A10) (Cat. No. IG4-MY2180) with a linear range of 0.5-31 ng/mL (QC tested).

 IgG4 Fc ELISA

Immobilized Monoclonal Anti-Human IL-13 Antibody, Human IgG4 at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human IgG4 Fc Antibody, Mouse IgG2a (1A10) (Cat. No. IG4-MY2180) with a linear range of 2-16 ng/mL (Routinely tested).

  • Background
    Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3).
  • Clinical and Translational Updates

Comments (0)


ETA des produits en stock: 2 jours ouvrables

Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

totop
Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
Fax
Fax
+1 888-377-6111
Address
Address
1 Innovation Way, Newark, DE 19711, USA

Leave a message