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Your Position: Home > Antibody > CD45RO > FABm021-01

PE-Labeled Monoclonal Anti-Human CD45RO Antibody, Mouse IgG2a (UCHL1) (0.03% Proclin)

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  • Application
    Flow Cytometry (Evaluation of the expression of CD45RO on Human cells).
  • Clone
    UCHL1
  • Species
    Mouse
  • Isotype
    Mouse IgG2a | Mouse Kappa
  • Specificity
    This product is a specific antibody specifically reacts with CD45RO protein.
  • Reactivity

    Human

  • Immunogen

    Purified Human CD45RO Protein.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Isotype Control

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM487 for product information.

  • Recommended Dilution
    1:20
  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin300 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
Bioactivity-FACS
 CD45RO FACS

Flow cytometric analysis of Jurkat staining with PE-Labeled Monoclonal Anti-Human CD45RO Antibody, Mouse IgG2a (UCHL1) (Cat. No. FABm021-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

Compared Data
 CD45RO COMPARED_DATA

Flow cytometric analysis of Jurkat staining with PE-Labeled Monoclonal Anti-Human CD45RO Antibody. PE signal was used to evaluate the binding activity of Anti-Human CD45RO Antibody. The biological activity level of ACRO is superior to competitor BL (Routinely tested).

  • Background
    CD45 is a glycoprotein with protein phosphatase activity abundantly expressed on the surface of all leukocytes. The protein is highly preserved during evolution and has been demonstrated even in chicken, sharks, and mosquitos. CD45 increases T-cell and B-cell receptor signaling as well as the development and function of leukocytes. Moreover, CD45 can reduce Toll-like receptors and cytokine signaling, as well as cell adhesion and migration in a cell type specific manner. In humans, six splice variants differing in the extracellular part of the molecule have been demonstrated. The human variants are termed CD45RABC (also named CD45R), CD45RAB, CD45RBC, CD45RA, CD45RB, and CD45RO, and are detected by subtype specific antibodies and molecular weight, respectively. CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells.
  • Clinical and Translational Updates

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ETA des produits en stock: 2 jours ouvrables

Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:3 Details
  • Latest Research Phase:Phase 3 Clinical

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