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Your Position: Home > Antibody > CD73 > FABm024-01

PE-Labeled Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) (0.03% Proclin)

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  • Source
    PE-Labeled Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) is a mouse monoclonal antibody recombinantly expressed from Hybridoma.
  • Application
    Flow Cytometry (Evaluation of the expression of CD73 on Human cells).
  • Species
    Mouse
  • Isotype
    Mouse IgG1
  • Specificity
    This product is a specific antibody specifically reacts with CD73 protein.
  • Immunogen

    Purified Human CD73 Protein.

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Isotype Control

    The Isotype control is sold separately and you can search for Cat. No. DNP-PM1 for product information.

  • Recommended Dilution
    1:20
  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4, 0.2% BSA, 0.03% Proclin300 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.
Bioactivity-FACS
 CD73 FACS

Flow cytometric analysis of MSC staining with PE-Labeled Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) (Cat. No. FABm024-01) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 1e6 cells in a final volume of 100 µL), compared with isotype control antibody. PE signal was used to evaluate the binding activity (QC tested).

  • Background
    5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (cluster of differentiation 73), is an enzyme that is encoded by the NT5E gene. CD73 commonly serves to convert AMP to adenosine. Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rare allelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.
  • Clinical and Translational Updates

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ETA des produits en stock: 2 jours ouvrables

Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:28 Details
  • Latest Research Phase:Phase 3 Clinical

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