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Your Position: Home > Protein > Glypican 1 > GP1-C52H3

Cynomolgus Glypican 1 / GPC1 Protein, His Tag

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  • Synonym
    Glypican 1,GPC1
  • Source
    Cynomolgus Glypican 1 Protein, His Tag(GP1-C52H3) is expressed from human 293 cells (HEK293). It contains AA Asp 24  - Ser 530 (Accession # XP_005574876.1).
    Predicted N-terminus: Asp 24
  • Molecular Characterization
    Glypican 1 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 57.8 kDa. The protein migrates as 60-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Glypican 1 SDS-PAGE

Cynomolgus Glypican 1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-ELISA
 Glypican 1 ELISA

Immobilized Human FGF basic, premium grade (Cat. No. BFF-H4117) at 1 μg/mL (100 μL/well) can bind Cynomolgus Glypican 1 Protein, His Tag (Cat. No. GP1-C52H3) with a linear range of 0.004-0.125 μg/mL (QC tested).

 Glypican 1 ELISA

Immobilized Cynomolgus Glypican 1 Protein, His Tag (Cat. No. GP1-C52H3) at 1 μg/mL (100 μL/well) can bind Biotinylated Human FGF basic, Avitag,His Tag (Cat. No. FGC-H81E3) with a linear range of 0.3-20 ng/mL (Routinely tested).

  • Background
    Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]
  • Clinical and Translational Updates

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 1 Clinical

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