로그인 회원가입
icon_bulk_order대량 주문 Acrobiosystems for English
0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Protein > CD89 > CD9-R82E3

Biotinylated Rhesus macaque CD89 / FCAR Protein, His,Avitag™ (MALS verified)

Order Now

  • Synonym
    CD89,FCAR,IgA Fc receptor
  • Source
    Biotinylated Rhesus macaque CD89 Protein, His,Avitag(CD9-R82E3) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asn 227 (Accession # F7H5K2-1).
    Predicted N-terminus: Gln 22
  • Molecular Characterization
    CD89 Structure

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 26.9 kDa. The protein migrates as 35-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
  • Protein Ratio
    Passed as determined by the HABA assay / binding ELISA.
  • Endotoxin
    Less than 1.0 EU per μg by the LAL method / rFC method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
CD89 SDS-PAGE

Biotinylated Rhesus macaque CD89 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
CD89 MALS images

The purity of Biotinylated Rhesus macaque CD89 Protein, His,Avitag (Cat. No. CD9-R82E3) is more than 90% and the molecular weight of this protein is around 40-60 kDa verified by SEC-MALS.

  • Background
    CD89 (FcαRI), encoded by the FCAR gene, is an IgA-specific receptor primarily expressed on myeloid cells (e.g., neutrophils, monocytes/macrophages). It mediates immune defense functions by binding to the Fc region of IgA (with a preference for polymeric forms), facilitating phagocytosis, antibody-dependent cellular cytotoxicity (ADCC), and inflammation regulation. Its signaling relies on the ITAM motif of the FcRγ chain, enabling dual immunoregulatory roles in both activation and suppression. Clinically, CD89 is implicated in IgA nephropathy, pathogen immune evasion, and tumor immunity. Targeted therapies, such as the bispecific antibody MOR202, are under development for diseases like multiple myeloma, highlighting its therapeutic potential as a bridge between mucosal and systemic immunity.
  • Clinical and Translational Updates

Comments (0)


ETA of in-stock products: 2 business days

Recommended Products
Streptavidin Coated Plates

Price(USD) : $32.00

Price(USD) : $137.00

Streptavidin-HRP

Price(USD) : $50.00

Price(USD) : $120.00

Magnetic Beads™ Streptavidin

Price(USD) : $138.00

Price(USD) : $230.00

Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:0 Details
  • Latest Research Phase:Preclinical

Datasheet & Documentation

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

totop